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from wikipedia

......... effects of methamphetamine use include:

• Compulsive fascination with useless repetitive tasks (see Punding)
• Severe psychological addiction
• Acne
• Depression
• Formication (false sensation of flesh crawling with bugs, with possible associated compulsive picking and infected sores)
• Amphetamine psychosis
• Erectile dysfunction ("Crystal cock")
• Long-term cognitive impairment due to neurotoxicity
• Tooth decay ("meth mouth")
• Damage to immune system
• Persistent anhedonia with chronic use
• Death
• Staphylococcus infection

The drug can stay in your system between three to four days

Side effects

Common side effects of methamphetamine include:

• Cardiovascular - Hypertension

• Endocrinal - Elevated body temperature

• Eye - Dilated pupils

• Gastrointestinal - Diarrhea, nausea

• Neuro-psychological - Paranoia, especially when mixed with cannabis.

• Neuro-psychological - Euphoria, followed by depression

• Skin - Rash

• Miscellaneous - Anorexia, insomnia, restlessness, weight loss

• Decrease in Appetite

Severe side effects (with chronic use) include:

• Amphetamine psychosis
• Clinical depression
• Kidney damage
• Liver damage

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From the Oregonian (Faces of Meth ): 

Theresa Baxter    June 2001                                     41 months later - using meth

Jennifer Lundgren   July 2003                                     17 months later - using meth

Nice!